Transcranial magnetic stimulation (TMS) is a noninvasive method to cause depolarization or hyper-polarization of the neurons in the brain. TMS uses electromagnetic induction to induce weak electric currents using a rapidly changing magnetic field; this can cause activity in specific or general parts of the brain, allowing for the study of brain function and interconnectivity.
- Neurophysiology– Examination of the physiology of the motor pathways in the central and peripheral nervous system.
- Neurology– Examination of functional aspects of motor nerve stimulation.
- Cognitive Neuroscience– The examination of human brain function.
Single pulse TMS causes neurons in the neocortex under the site of stimulation to depolarize and discharge an action potential. If used in the primary motor cortex, it produces muscle activity referred to as a motor evoked potential (MEP) which can be recorded on electromyography. If used on the occipital cortex, ‘phosphenes’ (flashes of light) might be perceived by the subject. In most other areas of the cortex, the participant does not consciously experience any effect, but behaviour may be slightly altered (e.g., slower reaction time on a cognitive task), or changes in brain activity may be detected using sensory equipment.
TMS can be used to measure the activity and function of specific brain circuits in humans. The most robust and widely accepted use is in measuring the connection between the primary motor cortex and a muscle to evaluate damage from stroke, multiple sclerosis, amyotrophic lateral sclerosis, movement disorders, motor neuron disease and injuries and other disorders affecting the facial and other cranial nerves and the spinal cord. TMS has been suggested as a means of measuring the internal pathways of the motor cortex by assessing short-interval intracortical inhibition (SICI), but this has yet to be validated.
DuoMAG MP features:-
- Controllable from coil controls, computer interface or external triggering
- Up to 2Hz repetition rate (0.5Hz at maximum output)
- Modular expansion for paired pulse TMS and/or high power single pulse stimulation through one coil
- External communications via TTL in/out triggers and USB.
- System control and configuration via Windows based touch-screen.
- Controllable from an external device.
- Custom protocol editor and storage by way of built-in computer.
- Supported by a complete range of circular, figure-8, focal and cone shaped coils.
The DuoMAG MP TMS transcranial magnetic stimulator is a CE-certified medical device for non-invasive brain stimulation in humans. It is limited to investigational and research use in USA.